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Valproate Depakote. Know the warning signs Learn the common signs of mental illness in adults and adolescents. Mental health conditions Learn more about common mental health conditions that affect millions. Symptoms of your condition that bother you the most If you have thoughts of suicide or harming yourself Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects If you experience side effects from your medications, discuss them with your provider.
Some side effects may pass with time, but others may require changes in the medication. Any other psychiatric or medical problems you have All other medications you are currently taking including over the counter products, herbal and nutritional supplements and any medication allergies you have Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication.
If you are pregnant, plan to become pregnant, or are breast-feeding If you drink alcohol or use illegal drugs How Should I Take Valproate?
Valproate is usually is taken times daily with or without food. Valproate tablets: Swallow whole. Do not crush, chew or split tablets. A specific treatment to reverse the effects of valproate does not exist. Platelets help the blood to clot.
Tell your doctor if this happens. Your doctor will monitor how much you eat and drink and check you for signs of dehydration, drowsiness, dizziness, and other side effects.
For children: Children younger than 2 years old have an increased risk of liver damage while taking this drug, especially if they also take other drugs to treat seizures. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:. Your body may process this drug more slowly and you may have more of a sedative effect. Too much of the drug in your body can cause dangerous effects.
This medication did not show effectiveness in children for mania. There is no evidence that divalproex is effective for long-term use in mania longer than three weeks. If your doctor would like you to take this drug for a longer period of time, they will check if you still need the drug regularly.
This medication did not show effectiveness in children for migraine prevention. For people with liver disease: If you have liver disease, you may not be able to process this drug as well as you should. You should avoid taking divalproex sodium if you have severe liver problems. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you.
Divalproex sodium oral tablet is used for long-term drug treatment. For manic episodes of bipolar disorder, your doctor will decide whether this is a short-term or long-term drug treatment. You may also experience more side effects from this drug if you take it on and off. If you take too much: Taking too much of this drug can cause dangerous effects, such as:. If your symptoms are severe, call or your local emergency services or go to the nearest emergency room right away.
What to do if you miss a dose: If you forget to take your dose of this drug, take it as soon as you remember. How to tell if the drug is working: For treatment of seizures: You should have fewer seizures. For treatment of manic episodes of bipolar disorder: You should see a decrease in symptoms caused by the manic phase of bipolar disorder. Your mood should be well-controlled. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled.
Your doctor will write the number of refills authorized on your prescription. There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
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Learn more about types of seizures, causes and symptoms, and how you can help someone having…. Health Conditions Discover Plan Connect. Divalproex Sodium, Oral Tablet. Divalproex sodium can cause liver failure that may be fatal, especially in children under age 2 and in people with liver problems caused by a genetic mitochondrial disorder.
Some people have thoughts about suicide while taking divalproex sodium. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Using divalproex sodium during pregnancy may increase the risk of serious birth defects that can develop early in pregnancy, even before you know you are pregnant. Using this medicine during pregnancy can also affect cognitive ability reasoning, intelligence, problem-solving later in your child's life. However, having a seizure during pregnancy could harm both the mother and the baby. If you take divalproex sodium for seizures or manic episodes: The benefit of preventing seizures or manic episodes may outweigh any risks posed by this medicine.
There may be other medications that are safer to use during pregnancy. Do not start or stop taking divalproex sodium without your doctor's advice. Do not use divalproex sodium to prevent migraine headaches if you are pregnant or you could become pregnant. If you are not pregnant, use effective birth control to prevent pregnancy while using divalproex sodium. Tell your doctor if you start or stop using hormonal contraception that contains estrogen birth control pills, injections, implants, skin patches, and vaginal rings.
Estrogen can interact with divalproex sodium and make it less effective in preventing seizures. It may not be safe to breastfeed while using this medicine.
Ask your doctor about any risk. Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling.
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Call your doctor at once if the person taking this medicine has signs of liver or pancreas problems, such as: loss of appetite, upper stomach pain that may spread to your back , ongoing nausea or vomiting, dark urine, swelling in the face, or jaundice yellowing of the skin or eyes.
Report any new or worsening symptoms to your doctor , such as: mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive mentally or physically , or have thoughts about suicide or hurting yourself.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
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